Medicines in capsules are generally powders or granules that are irritating to the esophagus and gastric mucosa, or have bad taste, are easily volatile, easily decomposed by saliva in the oral cavity, and are easily inhaled into the trachea. These medicines are packed into capsules, which not only protect the medicine from being destroyed, but also protect the digestive organs and respiratory tract. Removing the capsule shell may cause drug loss, drug waste, and reduced efficacy. In addition, some medicines need to be dissolved and absorbed in the intestine. Capsules are a kind of protection to protect the medicines from being destroyed by stomach acid. In medicine, it refers to a capsule made of special film-forming materials (such as gelatin, cellulose, polysaccharides, etc.), and the contents (such as powdered and liquid drugs, etc.) are filled into it in a dose to facilitate swallowing. , Of which gelatin capsules are the most popular two-section capsules in the world.
On April 15, 2012, some unscrupulous manufacturers in Hebei, Jiangxi, and Zhejiang were found to use heavy metal chromium-exceeding industrial gelatin as edible gelatin to produce medical capsules. According to CCTV News Channel, Zhejiang Xinchang County announced the results of random sampling of capsule raw materials and semi-finished products. The results showed that a total of 61 samples were taken from 4 companies that were seized to manufacture pharmaceutical capsules using industrial gelatin, including raw materials, semi-finished capsule products and finished capsule products. 29 batches were found to have excessive chromium content today 14 companies have drawn 39 samples, and 35 samples have been tested, and 4 batches have failed. In total, 96 batches of samples have been tested, and 33 samples have been detected with excessive chromium content.
Overnight, "leather capsules" on major microblogs and forums have become a hot topic, and many forums and websites have set them as keywords. This sudden report caused intense panic among the people, especially for the elderly and infirm. All relevant testing departments, as the gatekeepers of drug safety, shoulder a major mission. As one of the world's largest instrument manufacturers, Jena Company of Germany also shoulders the important mission of providing instruments with good stability and high precision for testing institutions. Jena Analytical Instruments has a history of more than 150 years in the field of optics. All optical components used in spectroscopic instruments are original ZEISS systems, and the quality of the instruments is well guaranteed. As early as 2006, the Zhejiang Provincial Institute of Drug Inspection took Jena's novAA 400 as a testing tool, and studied the determination of chromium in gelatin with reference to the European Pharmacopoeia and national standard chromium determination methods for food, and established a detailed determination The test plan for chromium in capsules has laid a solid foundation for controlling the chromium content of harmful elements in gelatin for capsules and tablets, and ensuring the safety of medication. The detailed experimental report can be downloaded at http: // #. For more information about applications and instruments, please visit the website http://www.jena.com.
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