Shanghai Haozhuang Instrument Co., Ltd. Haozhuang (LNB) brand freeze dryer is a vacuum freeze drying technology, referred to as freeze drying, also known as sublimation drying. Widely used in medicine, biological products, chemical industry and food industry. For heat-sensitive substances such as antibiotics, vaccines, blood products, enzyme hormones and other biological tissues, freeze-drying technology is very suitable.
Application advantages of freeze dryer:
There are various drying methods, such as sun drying, boiling drying, drying, spray drying and vacuum drying, etc., but ordinary drying methods are usually carried out at temperatures above 0 ℃ or higher. The dried products generally have the problems of shrinking volume and hardening texture. Most of the volatile components will be lost. Some heat-sensitive substances are denatured and deactivated, and some substances even oxidize. Therefore, compared with the product before drying, there is a big difference in the characteristics of the product after drying. The freeze-drying method is basically carried out below 0 ℃, that is, the product is frozen. Only when the residual moisture content of the product is reduced later, the product is allowed to rise to a temperature above 0 ℃, but generally does not exceed 40 ℃. Under vacuum, when the water vapor directly sublimates out, the drug remains in the ice shelf when it freezes, forming a sponge-like loose porous structure, so its volume is almost unchanged after drying. Before use again, as long as water for injection is added, it will immediately dissolve.
Compared with the conventional method, the freeze-drying method has the following advantages:
1. Many heat-sensitive substances will not be denatured or inactivated.
2. When drying at low temperature, some volatile components in the material lose little.
3. During the freeze-drying process, the growth of microorganisms and the action of enzymes cannot be carried out, so the original properties can be maintained.
4. Because it is dried in a frozen state, the volume is almost unchanged, the original structure is maintained, and the concentration phenomenon does not occur.
5. Since the water in the material exists in the form of ice crystals after pre-freezing, the dissolved substances of inorganic salts originally dissolved in water are evenly distributed in the material. During sublimation, the dissolved substances dissolved in water are precipitated, which avoids the surface hardening caused by the precipitation of inorganic salts carried by the internal moisture of the material to the surface in the general drying method.
6. The dried material is loose and porous, showing a sponge-like shape. After adding water, it dissolves quickly and completely, and the original properties are restored almost immediately.
7. Because the drying is carried out under vacuum, there is very little oxygen, so some easily oxidized substances are protected.
8. Drying can exclude more than 95% to 99% of moisture, so that the dried product can be stored for a long time without deterioration.
Shanghai Haozhuang Instrument Co., Ltd. specializes in the production of freeze dryers, with strong technical support, and wins by quality. The company provides you with professional freeze dryer installation, commissioning, maintenance services.
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