Chronic myeloid leukemia, also known as "slow granules". In the past, hematopoietic stem cell transplantation was the only way to cure slow granules, but it was also quite limited. Professor Li Junmin, director of the Department of Hematology, Ruijin Hospital, Shanghai Jiaotong University School of Medicine, said: "At present, the internationally recognized use of molecular targeted drugs tyrosine kinase inhibitors has become the first-line option for slow-grain therapy."
According to statistics, the incidence of chronic myeloid leukemia in China is about 0.36 per 100,000 people. Chinese patients with chronic myelogenous leukemia are younger than those in the West. Domestic epidemiological surveys show that the median age of chronic myeloid leukemia is 45- 50 years old. Patients may experience increased white blood cell counts, splenomegaly, and weight loss. Professor Li introduced: "Stem cell transplantation is affected by various factors such as the availability of donors and the age of patients. The Chinese chronic myeloid leukemia guidelines have made drug treatment the first-line option for slow-grain therapy. As long as the treatment is standardized and regularly monitored, some Patients are expected to achieve the desired results. "
At the same time, Professor Wang Aihua of the Department of Hematology, Ruijin Hospital added: "Monitoring" is particularly important for the treatment of slow-grain. At present, polymerase chain reaction (PCR) is a commonly used experimental method in molecular testing, and sampling can usually be completed together with routine blood tests. Regular PCR efficacy monitoring can help detect possible remission or compliance problems early and help optimize treatment options. Therefore, patients with chronic myeloid leukemia should go to the hospital every 3 months for relevant examinations, so as to know whether the condition is well controlled. "
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